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  • A recombinant agent, which is chemically identical or similar to the endogenous cytokine interleukin-17 (IL-17). IL-17 is produced by cytotoxic T cells and stimulates stromal cells to produce pro-inflammatory and hematopoietic cytokines. This cytokine enhances expression of IL-6, IL-8, and ICAM-1 in fibroblasts and appears to induce osteoclastogenesis.
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