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  • A recombinant agent, which is chemically identical to or similar to the endogenous protein Fas ligand OX40, a member of the tumor necrosis factor (TNF) family. Expressed by antigen presenting cells (APC), OX40 ligand binds to the OX40 receptor on CD4 T-cells, thereby priming antigen-specific activation of CD4 T-cells and inducing CD4 T-cell secretion of interleukin 4 (IL-4). (NCI04)
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