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  • Formulated therapeutic analogs of one of a number of endogenous chemotactic polypeptide cytokines. Beta chemokine is synthesized and released by macrophages, endothelial cells, keratinocytes, fibroblasts, and smooth muscle cells in response to infection or tissue damage, recruiting circulating macrophages to sites of production. This agent may regulate tumor growth by modulating tumor-associated angiogenesis and metastasis and may either promote or inhibit tumor growth. (NCI04)
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