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  • A topical solution containing phenylephrine, a sympathomimetic amine with vasoconstricting activity. Upon topical application to the oral mucosa, phenylephrine may activate alpha-adrenergic receptors in the mucosa thereby causing vasoconstriction. As a result, this agent may reduce swelling of the mucosal membranes and decrease radiotherapy-induced mucositis. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C91075\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C91075\' NCI Thesaurus)
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