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  • Human MLLT3 wild-type allele is located in the vicinity of 9p22 and is approximately 281 kb in length. This allele, which encodes protein AF-9, plays a role in modulation of transcription by RNA polymerase II (Gene Ontology/GO). Acute nonlymphocytic leukemia is associated with the translocation t(9;11)(p22;q23) of this gene and the MLL gene.
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