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  • Human RRAS2 wild-type allele is located in the vicinity of 11p15.2 and is approximately 80 kb in length. This allele, which encodes Ras-related protein R-Ras2, may play a role in both phosphatidylinositol-mediated signal transduction and nuclear factor kappa B complex pathway attenuation. A point mutation in the gene is associated with ovarian cancer.
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