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  • Human SETDB1 wild-type allele is located within 1q21 and is approximately 38 kb in length. This allele, which encodes histone-lysine N-methyltransferase, H3 lysine-9 specific 4 protein, plays a role in the methylation of histone H3 at lysine-9, a specific tag for epigenetic transcriptional repression.
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