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  • Human MAP3K14 wild-type allele is located in the vicinity of 17q21 and is approximately 54 kb in length. This allele, which encodes mitogen-activated protein kinase kinase kinase 14 protein, plays a role in the modulation of signaling cascades mediated by tumor-necrosis/nerve-growth factor family receptors and the interleukin-1 type-I receptor.
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