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  • Human PAX7 wild-type allele is located within 1p36.2-p36.12 and is approximately 105 kb in length. This allele, which encodes paired box gene Pax-7 protein, plays a role in both fetal neural crest formation and myoblast differentiation. In alveolar rhabdomyosarcoma, the wild-type allele is involved in a translocation t(1;13)(p36;q14) with the FOXO1 wild-type allele.
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