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Human XAGE2 wild-type allele is located in the vicinity of Xp11.22 and is approximately 7 kb in length. This allele, which encodes G antigen family D member 3 protein, may be involved in the modulation of testicular functions. The gene is expressed aberrantly in Ewing\'s sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor.
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