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  • Human RIPK2 wild-type allele is located within 8q21 and is approximately 33 kb in length. This allele, which encodes receptor-interacting serine/threonine-protein kinase 2 protein, plays a role in promotion of apoptosis, activation of the transcription factor NF-kappa-B, and signaling involved in both the innate and adaptive immune response pathways.
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