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  • Human CCKBR wild-type allele is located in the vicinity of 11p15.4 and is approximately 12 kb in length. This allele, which encodes gastrin/cholecystokinin type B receptor protein, plays a role in modulating the regulatory peptides of the brain and gastrointestinal tract. A misspliced transcript allelic variant that includes an intron has been identified in cells from colorectal and pancreatic tumors.
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