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Human MAGED1 wild-type allele is located in the vicinity of Xp11.23 and is approximately 9 kb in length. This allele, which encodes melanoma-associated antigen D1 protein, is involved in the regulation of tumor specific antigens in the p75 neurotrophin receptor mediated programmed cell death pathway and is a member of the melanoma antigen gene (MAGE) family.
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