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  • Human TAL2 wild-type allele is located in the vicinity of 9q32 and is approximately 1 kb in length. This allele, which encodes T-cell acute lymphocytic leukemia-2 protein, may play a role in the modulation of transcription by RNA polymerase II. T-cell acute lymphoblastic leukemia is linked with the translocation t(7;9)(q34;q32) of the enhancer of the T-cell receptor beta gene and this gene.
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