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  • Anaphylaxis is an acute systemic reaction characterized by pruritus, generalized flush, urticaria, respiratory distress and vascular collapse. It occurs in a previously sensitized person upon re-exposure to the sensitizing antigen. Other signs and symptoms include agitation, palpitation, parasthesias, wheezing, angioedema, coughing, sneezing and difficulty breathing due to laryngeal spasm or bronchospasm. Less frequent clinical presentations may include seizures, vomiting, abdominal cramps and incontinence.1
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