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  • Biopsy trephines designed to cut and remove circular sections of bone marrow (a cone of bone and marrow) typically from the hip bone (usually from the anterior superior iliac spine below the iliac crest) that are intended for laboratory examination and/or test with minimal sample and surrounding tissue damage. These trephines are typically handheld, manual instruments consisting of large (at least 5 to 7 mm) hollow cylinders with a circular-saw-like serrated working edge attached to a handle; the procedure is frequently performed immediately after bone marrow aspiration using a fine needle. Core bone marrow samples can be obtained using bone marrow core needles. Bone marrow biopsy trephines are used to obtain histologic samples for morphological assessment of the marrow.
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