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Containment glove boxes designed to provide a confined atmosphere to protect the operator and the environment from highly toxic biohazardous materials inside. These boxes are typically made of stainless steel, one-piece molded plastic, or plastic with a stainless steel liner. They include more safety devices and mechanisms than standard containment glove boxes, such as a ventilation system with one or more high-efficiency particulate-air (HEPA) or ultra-low particulate-air (ULPA) filters both at the input and output of the box, and a secondary HEPA, ULPA, or carbon filter (for particulates or gaseous contaminants, respectively) in the exhaust system. Most of these boxes include blowers to permit outside exhaust when required for a particular application and gloves and/or sleeves (e.g., neoprene, butyl, Hypalon) appropriate for the material being processed. Some boxes can accommodate an analytical balance for safe weighing of biohazardous materials, and other equipment (e.g., moisture analyzers). Biohazardous material glove boxes are used in laboratories and clinical pharmacies to process dangerous or potentially dangerous products; special boxes are available for processing carcinogenic materials, chemotherapy drugs, and low-level gaseous or particulate radioisotopes.
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