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  • Extravasation of drug product administered by venous access is a local complication and can be associated with pain and swelling. Some products may be associated with more serious sequelae including tissues necrosis. May be caused by: damage to the posterior wall of the vein or occlusion of the vein proximal to the injection site; occlusion of vein proximal to injection site. Extravasation is broadly defined as discharge or escape of blood or other fluid normally found in a vessel or tube, into the surrounding tissues. For purposes of this SMQ, \'extravasation\' relates to complication of drug delivery (injection, infusion, etc.) or to a device (includes potential sequelae of extravasation). Pain, erythema, and swelling are typically observed.
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