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  • A radioimmunoconjugate comprised of the chimeric monoclonal antibody girentuximab conjugated with the gamma-emitting radioisotope indium In 111. Indium In 111-DOTA-girentuximab binds to G250, allowing the localization of G250-expressing tumor cells using gamma scintigraphy.Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA). Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C74047\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74047\' NCI Thesaurus)
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