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Hemostatic agents designed for intraoperative control of organ and/or tissue bleeding (i.e., hemorrhage) during surgical procedures. These agents may consist of products intended to control bleeding and/or to seal tissues (usually fibrin and/or synthetic absorbable sealants); non-absorbable biological adhesives; or non-absorbable synthetic glues that usually consist of cyanoacrylate compounds. Surgical hemostatic agents are intended mainly to facilitate permanent bleeding control in organs, tissues, and the vasculature. They are also designed to facilitate recovery after surgery and to help avoid additional surgical procedures. They may be also used in some emergency situations (e.g., to stop hemorrhage in open wounds).
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