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  • Stage IIB includes: (T4a, N0, M0); (T3, N1, M0); (T2, N2, M0); (T1, N3, M0). T1: tumor invades lamina propria, muscularis mucosae, or submucosa. T2: tumor invades the muscularis propria. T3: tumor penetrates subserosal connective tissue without invasion of visceral peritoneum or adjacent structures. T4a: tumor invades serosa (visceral peritoneum). N0: No regional lymph node metastasis. N1: metastasis in 1-2 regional lymph nodes. N2: metastasis in 3-6 regional lymph nodes. N3: metastasis in seven or more regional lymph nodes. M0: no distant metastasis. (AJCC 7th ed.) Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C87776\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C87776\' NCI Thesaurus)
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