PropertyValue
?:definition
  • A technetium Tc 99m radiopharmaceutical of a glutamate-rich peptide (GP) conjugated, via carbodiimide linker, to the heparin-like polysaccharide chitosan (CH) in a 1:1 ratio, with potential tumor targeting property. Upon administration, 99m Tc-glycopeptide targets and is taken up by glutamate-specific transporters on tumor cells. Upon internalization, the Tc99m moiety can be visualized upon scanning. GP may potentially be used as a drug carrier for antineoplastic drug delivery to tumor cells. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C91737\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C91737\' NCI Thesaurus)
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C2984525_PDQ>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C2984525_PDQ>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all