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  • Stage III includes: IIIA (T3, N0, M0); IIIB (T1-3, N1, M0). T3: Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts. T1: Tumor invades lamina propria or muscular layer. T2: Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver. N0: No regional lymph node metastasis. N1: Metastases to nodes along the cystic duct, common bile duct, hepatic artery, and/or portal vein. M0: No distant metastasis. (from AJCC 7th Ed.)
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