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  • Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. [GOC:BHF, PMID:11526399, PMID:11544529, PMID:12447442]
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