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A topical preparation of the fat-soluble vitamin E with potential antioxidant and cytoprotective activities. As a potent antioxidant and radical scavenger, vitamin E ameliorates free-radical damage to cell membranes, thereby protecting cells from reactive oxygen species and maintaining the integrity of cellular macromolecules. In addition, vitamin E noncompetitively inhibits cyclooxygenase (COX) activity in many tissues, which may decrease inflammation. Vitamin E is a generic name for a group of compounds known as tocopherols and tocotrienols (tocols). Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C67081\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67081\' NCI Thesaurus)
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