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  • **Description:**The interaction of entities whereupon a subject entity is brought into proximity to a physical, chemical or biological agent. This includes intended exposure (e.g. administering a drug product) as well as accidental or environmental exposure. (Note: This class deals only with proximity and not the effectiveness of the exposure, i.e. not all exposed will suffer actual harm or benefit.)

    **Examples:**Exposure to radiation, drug administration, inhalation of peanut aerosol or viral particles.

  • The action of coming into sufficient physical proximity to allow physical or chemical interaction. Examples include: exposure to radiation, inhalation of peanut aerosol or viral particles. This includes intended exposure (e.g. administering a drug product) as well as accidental or environmental exposure. Actual vs. potential exposure can be differentiated using Act.uncertaintyCode.

    The agent to which the subject was exposed is conveyed as aDirectparticipation or specialization there-of.Constraints:The following Participations should be used with the following Roles and Entities to distinguish the specific entities:

    * The ***exposed entity*** is the entity of interest that is the recipient of the exposure and potentially affected. This is conveyed through the subject (SBJ) Participation. * An entity that has carried the agent transmitted in the exposure is the \'***exposure source***\' (EXSRC). For example: * a person or animal who carried an infectious disease and interacts (EXSRC) with another person or animal (SBJ) transmitting the disease agent; or * a place or other environment (EXSRC) and a person or animal (SBJ) who is exposed in the presence of this environment. * When it is unknown whether a participating entity is the source of the agent (EXSRC) or the target of the transmission (SBJ), also known as \'***exposure contact***\', the \'participant\' (PART) is used. * The substance to which the subject is exposed that carries the exposure agent or the chemical substance of interest itself, participates as a \'consumable\' (CSM). There are at least two configurations: (a) the player of the Role that participates as CSM is the chemical or biological substance mixed or carried by the scoper-entity of the Role (e.g., ingredient role); or (b) the player of the Role that participates as CSM is a mixture known to contain the chemical, radiological or biological substance of interest. * The device specifically used to administer the substance is associated using the device (DEV) Participation. This may be a device intentionally used (such as applicator device) or it may be a thing that accidentally carried this substance; for instance, an infected needle or knife. The same entity may be related in the act as both EXSRC and DEV.

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