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  • OBSOLETE. The post-transcriptional removal by a virus of the 5\' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5\' triphosphates; removal by the virus of the 5\'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition. [PMID:18446221, VZ:856]
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