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  • Penetration without perfusion. Contrast material passes beyond the area of obstruction but \'hangs up\' and fails to opacify the entire coronary bed distal to the obstruction for the duration of the cineangiographic filming sequence. (Chesebro JH, Knatterud GL, Roberts R, et al, Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase: Clinical findings through hospital discharge, Circulation 76, No. 1, 142-154, 1987)
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