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  • Human CCNB1IP1 wild-type allele is located in the vicinity of 14q11.2 and is approximately 22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CCNB1IP1 protein, is involved in the modulation of both protein ubiquitination and cell cycle progression. A translocation of the HMGA2 gene and this gene may be associated with leiomyoma.
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