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  • Human GOPC wild-type allele is located in the vicinity of 6q21 and is approximately 284 kb in length. This allele, which encodes Golgi-associated PDZ and coiled-coil motif-containing protein, is involved in the regulation of intracellular protein transport. A chromosomal deletion del(6q21) fuses this gene and the ROS1 gene and is associated with glioblastoma multiforme.
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