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  • Human HSP90AB1 wild-type allele is located in the vicinity of 6p12 and is approximately 7 kb in length. This allele, which encodes heat shock protein HSP 90-beta, is involved in the regulation of both protein folding and interferon signaling. A chromosomal translocation t(3;6)(q27;p12) of this gene and the BCL6 gene is associated with B cell non-Hodgkin lymphoma.
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