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  • Human TFPT wild-type allele is located in the vicinity of 19q13 and is approximately 9 kb in length. This allele, which encodes TCF3 fusion partner protein, is involved in the positive regulation of apoptosis. A chromosomal inversion inv(19)(p13;q13) of this gene and the TCF3 gene is associated with pre-B-cell acute lymphoblastic leukemia.
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