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  • Human TNFRSF17 wild-type allele is located in the vicinity of 16p13.1 and is approximately 3 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 17 protein, plays a role in cytokine binding and signaling pathways. A chromosomal translocation t(4;16)(q26;p13) of this gene and the IL2 gene is associated with T-cell acute lymphoblastic leukemia.
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