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  • Human SH3D19 wild-type allele is located in the vicinity of 4q31.3 and is approximately 108 kb in length. This allele, which encodes SH3 domain-containing protein 19, plays a role in both protein-protein interactions and protein localization to the plasma membrane. A translocation involving this gene and the RUNX1 gene may be associated with acute myeloid leukemia.
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