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  • Human DIRC3 wild-type allele is located in the vicinity of 2q35 and is approximately 473 kb in length. This allele, which encodes disrupted in renal carcinoma 3 transcript, may play a role in renal cell carcinoma. A chromosomal translocation t(2;3)(q35;q21) of this gene and the HSPBAP1 gene is associated with renal cell carcinoma.
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