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  • Human HSPBAP1 wild-type allele is located in the vicinity of 3q21.1 and is approximately 54 kb in length. This allele, which encodes HSPB1-associated protein 1, may be involved in the regulation of the response to cell stress. A chromosomal translocation t(2;3)(q35;q21) of this gene and the DIRC3 gene is associated with renal cell carcinoma.
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