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  • Human MRE11 wild-type allele is located in the vicinity of 11q21 and is approximately 77 kb in length. This allele, which encodes double-strand break repair protein MRE11A, is involved in the modulation of DNA recombination, telomere maintenance and double-strand break repair. Mutation of the gene is associated with ataxia telangiectasia-like disorder.
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