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  • refers to the lateral agranular insular area, a subdivision of the orbitomedial prefrontal cortex (macaque). It is defined on the basis of internal structure and connectivity. Located in the posterior portion of the orbital gyri, area Ial is one of three subdivisions of the lateral agranular insular region. Identifying structural features of area Ial are radial striations observed by Nissl stain in the internal pyramidal layer (V) and two dense bands revealed by Timm stain in the external pyramidal layer (II/III) and the internal pyramidal layer (V). The other two lateral agranular areas are area Iai (macaque) and area Iapl (macaque) ( Carmichael-1994 ). Its equivalent in the human is area Ial ( Ongur-2003 ). As a component of insulo-orbital agranular cortex, its equivalent in the rat and mouse would be in the agranular insular cortex.
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