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  • Human CYP26B1 wild-type allele is located in the vicinity of 2p13.2 and is approximately 19 kb in length. This allele, which encodes cytochrome P450 26B1 protein, is involved in the specific inactivation of all-trans-retinoic acid. Mutations in this gene are associated with craniofacial and other skeletal anomalies.
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