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  • refers to one of two parts of the granular insula reported by some authors in the human. It has been defined by automated analysis of images of silver-stained coronal sections ( Kurth-2010a ). Located in the posterodorsal portion of the long insular gyri, rostral to the other part, area Ig1 of Kurth, it is defined by automated analysis of silver-stained coronal sections. Both parts are distinguished by a well-developed internal granular layer (IV). Area Ig2 is distinguished from area Ig1 of Kurth, by a narrower external granular layer (II), a bifurcated external pyramidal layer (III), and a more distinct internal pyramidal layer (V). A contemporary study in the human conducted manually on the basis of multiple stains did not report subdivision of the granular insula ( Morel-2013 ). Results of studies in the macaque are also mixed. Area Ig2 of Gallay ( Gallay-2012 ), identified on the basis of multiple stains, showed a similar stratification of pyramidal layer (III), but it differed topologically from area Ig1 of Kurth in the human. It was located caudodorsally to Ig1 of Gallay, whereas Ig2 of Kurth was located rostroventrally to Ig1 of Kurth. Subdivision of the granular insula was not reported in other studies of the macaque ( Mesulam-1984, Paxinos-2009a ), nor of the rat ( Swanson-2004 ) or mouse ( Hof-2000 ).
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