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  • Electron microscopy stains designed to provide contrast to the specimen using ruthenium tetroxide. These electron microscopy stains are quite volatile and aggressive oxidants. Ruthenium tetroxide stains saturated and unsaturated polymer materials as well as stabilizing thin sections under the bombardment of the electron beam; some can produce either a positive or a negative stain. They are used as fixation/staining agents for electron microscopy.
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