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  • Peripheral-nerve electrical stimulators that apply periodic low-level stimuli to the vagus nerve with appropriate characteristics (e.g., frequency, pulse shape) to block the nerve signals. These stimulators consist of a pulse generator typically implanted subcutaneously and lead wires that run to electrodes placed on the anterior and posterior abdominal trunks of the vagus nerve (just above the junction between the esophagus and the stomach). The stimulator also includes an external battery-powered controller. Vagus nerve blocking electrical stimulators are mainly intended to induce weight loss in overweight patients by increasing the sensation of full-feeling (i.e., satiety); the stimulators may be also used in the treatment of other gastrointestinal disorders.
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