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  • Topical solutions and creams designed to produce temporary local anesthetic effects in a small external area of the body without causing any metabolic effect. These products usually consist of a solution with some chemical components (e.g., ethyl chloride, solutions combining pentafluoropropane and tetrafluoroethane) which evaporate quickly, removing heat from the area where it is applied. The rapid evaporation causes a cooling effect that acts as a local anesthetic. Anesthetic topical solutions/creams may be used before needle procedures (e.g., injection) and/or minor surgeries. Topical anesthetic solutions and creams that are absorbed by the tissues and may produce considerable metabolic effects (e.g., lidocaine) are not included under this category of solutions.
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