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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids (e.g., plasma) to determine the level of the protein procalcitonin (PCT), a prohormone of the hormone calcitonin, that can be produced by several cell types and many organs and circulates in plasma. Procalcitonin levels increase rapidly (values in normal people are usually below 0.1 ng/mL) in response to pro-inflammatory stimuli, in particular those produced by bacterial products. The evaluation of PCT concentration facilitates the assessment of the patient\'s risk of progression to severe sepsis and septic shock; localized infections, allergic disorders, transplant rejection, and other diseases do not usually induce significant increases in the PCT value above 0.5 ng/mL.
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