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Molecular assay reagents intended to identify mutations in the Wilms tumor 1 (WT1) gene, located at chromosome 11p13, which encodes for a transcription factor essential to the normal development of the urogenital system. This inherited genetic mutation has been identified in patients with predisposition to Wilms\' tumor (nephroblastoma) type 1 (WT1); it is also associated with Denys-Drash and Frasier syndromes.
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