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  • Molecular assay reagents intended to identify mutations in the cyclin D1 (CCND1) gene, located at chromosome 11q13.3, which is essential for control of the cell cycle at the G1/S (start) transition. Genetic rearrangements or amplifications that increase the expression of this gene have been identified in patients with B-cell lymphocytic malignancies, particularly mantle cell lymphoma (MCL) and parathyroid adenomatosis type 1 (PRAD1).
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