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Molecular assay reagents intended to identify mutations in the breast cancer 2 (BRCA2) gene, located at chromosome 13q12.3; these mutations facilitate cellular response to DNA repair. BRCA1 functions with BRCA2 in the repair of damaged DNA. Mutations at this locus have been identified in patients with increased risk of breast cancer, Fanconi anemia, and ovarian, prostate, and pancreatic cancer.
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