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  • Molecular assay reagents intended to identify mutations in the breast cancer 1 (BRCA1) gene, located at chromosome 17q21; these mutations facilitate cellular response to DNA repair. BRCA1 functions with BRCA2 in the repair of damaged DNA. Mutations at this locus have been identified in patients with familial breast cancer and genetic susceptibility to familial breast and/or breast-ovarian cancer.
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