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Molecular assay reagents intended to identify mutations in the adenomatous polyposis coli (APC) tumor suppressor gene, located at chromosome 5q21, which encodes for a tumor suppressor protein. Mutations at this locus have been identified in patients with familial adenomatous polyposis (FAP); Gardner\'s syndrome (GS); hereditary desmoid disease (HDD), which is also known as familial infiltrative fibromatosis (FIF); and Turcot\'s syndrome.
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