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Molecular assay reagents intended for use in identifying the acquired presence of three copies of chromosome 8 in a patient sample, rather than the normal two (i.e., trisomy 8). Acquired trisomy 8 is associated with chronic myelogenous leukemia and other chronic myeloproliferative diseases (e.g., polycythemia vera, idiopathic myelofibrosis), myelodysplastic syndromes, and acute nonlymphocytic leukemias.
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